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Ann Thorac Surg 1989;48:413-416
© 1989 The Society of Thoracic Surgeons


Articles

Long-Term Results After Surgical Repair of Incomplete Endocardial Cushion Defects

Eric L. Ceithaml, MD*, Frank M. Midgley, MD, Lowell W. Perry, MD

Division of Cardiothoracic Surgery, University Hospital, and Department of Surgery, University of Florida College of Medicine, Jacksonville, Florida; Department of Cardiovascular Surgery, Children's Hospital National Medical Center, Washington, DC; and Department of Surgery and Department of Child Health and Development, George Washington University, Washington, DC

Accepted for publication June 12, 1989.

* Address reprint requests to Dr Ceithaml, University Hospital of Jacksonville, 655 West 8th Street, Jacksonville, FL 32209


    Abstract
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 Abstract
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Since 1964, 56 children (mean age, 6.7 years) underwent repair of incomplete endocardial cushion defects. Forty patients had isolated ostium primum defects. Additional congenital defects were present in 17 patients (30%). All patients underwent patch closure of the ostium primum defect and 47 of 56 patients (84%) underwent mitral valvuloplasty. Hospital mortality was 1.8% (one death). Arrhythmias developed in 7 other patients in the early postoperative period, of which six were transient and resolved completely. One patient required early pacemaker placement for complete heart block. Cumulative follow-up was 378 patient-years. There were three late deaths (5.7%), and additional operations were required in 12 patients (22.6%). Seven of these 12 patients required mitral valve replacement for severe mitral regurgitation. The mean interval between initial repair and mitral valve replacement was 4.2 years, with only three valves needing replacement within 12 months. There was a significant correlation between the severity of mitral regurgitation before initial repair and subsequent need for mitral valve replacement. Late onset atrial arrhythmias have developed in 6 patients. Current functional status has been evaluated in 50 of 52 surviving patients and 88.5% are in NYHA class I, with the remainder in class II.


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 Abstract
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  1. Losay J, Rosenthal A, Castaneda AR, Bernard WH, Nadas AS. Repair of atrial septal defect primum J Thorac Cardiovasc Surg 1978;75:248-254.[Abstract]
  2. McMullan MH, McGoon DC, Wallace RB, Danielson GK, Weidman WH. Surgical treatment of partial atrioventricular canal Arch Surg 1973;107:705-710.[Medline]
  3. Pillai R, Ho SY, Anderson RH, Lincoln C. Ostium primum atrioventricular septal defect: an anatomical and surgical review Ann Thorac Surg 1986;41:458-461.[Abstract/Free Full Text]
  4. King RM, Puga FJ, Danielson GK, Schaff HC, Julsrud PR, Feldt RH. Prognostic factors and surgical treatment of partial atrioventricular canal Circulation 1986;74(Suppl 1):42-46.
  5. Pagon RA, Graham Jr JM, Zonana J, Yong SL. Coloboma, congenital heart disease, and choanal atresia with multiple anomalies: CHARGE association J Pediatr 1981;99:223-227.[Medline]
  6. Portman MA, Beder SD, Ankeney JL, VanHeeckeren O, Liebman J, Riemenschneider TA. A 20 year review of ostium primum defect repair in children Am Heart J 1985;110:1054-1058.[Medline]
  7. Levy S, Blondeau P, Dubost C. Long-term follow-up after surgical correction of the partial form of common atrioventricular canal (ostium primum) J Thorac Cardiovasc Surg 1974;67:353-363.[Medline]
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This Article
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Right arrow Articles by Ceithaml, E. L.
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