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Ann Thorac Surg 1988;45:638-642
© 1988 The Society of Thoracic Surgeons

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Articles

Determination of Brain Temperatures for Safe Circulatory Arrest during Cardiovascular Operation

Department of Surgery and the Section of Neurophysiology, Department of Neurology, Baylor College of Medicine and The Methodist Hospital, Houston, TX

^* Address reprint requests to Dr. Coselli, 6535 Fannin St, M.S. B-405, Houston, TX 77030

	Abstract

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Profound hypothermia protects cerebral function during circulatory arrest in the surgical treatment of a variety of cardiac and aortic abnormalities. Despite its importance, techniques to determine the appropriate level of hypothermia vary; studies of temperatures recorded from multiple peripheral body sites show inconsistent findings. The purpose of this study is to establish objective criteria to consistently identify intraoperatively the safe level of hypothermia. Our studies are based on experimental evidence showing a correlation between brain temperature and development of electrocerebral silence (ECS) on the electroencephalogram (EEG), and the recognition that the EEG, as an objective measure of brain function, can easily be recorded intraoperatively. We studied 56 patients who required circulatory arrest during operation for replacement of the ascending aorta or aortic arch (N = 55) or aortic valve replacement (N = 1). Peripheral body temperatures from the nasopharynx, esophagus, and rectum and the EEG were continuously recorded during body cooling. Circulatory arrest time ranged from 14 to 109 minutes. No peripheral body temperature from a single site or from a combination of sites consistently predicted ECS. There was a wide variation in temperature among body sites when ECS occurred: nasopharyngeal, 10.1° to 24.1°C; esophageal, 7.2° to 23.1°C; rectal, 12.8° to 28.6°C. Fifty-one (91%) of the 56 patients survived. Three had neurological deficits, none clearly related to hypothermia. Two patients (3.6%) required reexploration for postoperative bleeding. We conclude that monitoring the EEG to identify ECS is a safe, consistent, and objective method of determining the appropriate level of hypothermia.

	Footnotes

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Presented at the Thirty-fourth Annual Meeting of the Southern Thoracic Surgical Association, Boca Raton, FL, Nov 5–7, 1987.

We gratefully acknowledge the assistance of Miss Elisa Manti in the preparation of the manuscript and the technical assistance of Lisa Rhodes and Elna Robinson, R.EEG T., in intraoperative recording.

	References

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