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Ann Thorac Surg 1987;44:62-65
© 1987 The Society of Thoracic Surgeons


Articles

Long-term Fate of the Diaphragm Surgically Plicated During Infancy and Early Childhood

Kenneth S. Stone, M.D., John W. Brown, M.D., David F. Canal, M.D., Harold King, M.D.

From the Department of Surgery, Cardiovascular and General Surgery Sections, Indiana University Medical Center, Indianapolis, IN

Accepted for publication December 12, 1986.


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 Abstract
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Favorable early results have been reported utilizing transthoracic diaphragmatic plication in symptomatic children with phrenic nerve injury. However, little has been published about the late functional results of this technique. Since 1976, 10 of 3,000 patients operated on for congenital heart disease have sustained phrenic nerve injury with subsequent respiratory embarrassment. An additional patient sustained phrenic nerve injury as a result of birth trauma. The diagnosis was confirmed by paradoxical diaphragmatic motion on fluoroscopy. All but 2 patients were less than 5 months old at the time of diaphragmatic plication, and the average weight was 5.4 kg. The indication for diaphragmatic plication was inability to wean from the ventilator in 8 of the 11 patients and persistent postoperative tachypnea, stridor, and CO2 retention in the remaining 3 patients. A more aggressive approach to diagnosis and operative treatment since 1980 has resulted in a substantially shorter duration of endotracheal intubation and a shorter stay in the intensive care unit. Diaphragmatic fluoroscopy 1 to 7 years postoperatively has demonstrated return of normal function in 6 of 6 patients studied.


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Address reprint requests to Dr. Brown, Department of Surgery, Indiana University Medical Center, 545 Barnhill Dr/EM 212, Indianapolis, IN 46223.


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  1. Shoemaker R, Palmer G, Brown JW, King H. Aggressive treatment of acquired phrenic nerve paralysis in infants and small children Ann Thorac Surg 1981;32:251.[Abstract/Free Full Text]
  2. Richard J, Chevalier V, Capelle R, et al. La paralysie dia-phragmatique obstétricale Arch Fr Pediatr 1957;14:563.[Medline]
  3. Stauffer UG, Rickham PP. Acquired eventration of the diaphragm in the newborn J Pediatr Surg 1972;7:635.[Medline]
  4. Wayne ER, Campbell JB, Burrington JD, Davis WS. Eventration of the diaphragm J Pediatr Surg 1974;9:643.[Medline]
  5. Bishop HC, Koop CE. Acquired eventration of the diaphragm in infancy Pediatrics 1958;22:1088.[Abstract/Free Full Text]
  6. Sethi G, Reed WA. Diaphragmatic malfunction in neonates and infants J Thorac Cardiovasc Surg 1971;62:138.[Medline]
  7. Greene W, L'Hereux P, Hunt CE. Paralysis of the diaphragm Am J Dis Child 1975;129:1402.[Medline]
  8. Schwartz MZ, Filler RM. Plication of the diaphragm for symptomatic phrenic nerve paralysis J Pediatr Surg 1978;13:259.[Medline]
  9. Mickell JJ, Oh KS, Siewers RD, et al. Clinical implications of postoperative unilateral phrenic nerve paralysis J Thorac Cardiovasc Surg 1978;76:297.[Abstract]
  10. Mearns AJ. Iatrogenic injury to the phrenic nerve in infants and young children Br J Surg 1977;64:558.[Medline]
  11. Weldon CS: Discussion of Mickell et al [9].
  12. France NE. Unilateral diaphragmatic paralysis and Erb's palsy in the newborn Arch Dis Child 1954;29:357.[Free Full Text]
  13. Haller A, Pickard L, Tepas J, et al. Management of diaphragmatic paralysis in infants with special emphasis on selection of patients for operative plication J Pediatr Surg 1979;14:779.[Medline]
  14. Jewett Jr TC, Thomson Jr NB. Iatrogenic eventration of the diaphragm in infancy J Thorac Cardiovasc Surg 1964;48:801.
  15. Othersen Jr HB, Lorenzo RL. Diaphragmatic paralysis eventration: newer approaches to diagnosis and operative correction J Pediatr Surg 1977;12:309.[Medline]



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