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Ann Thorac Surg 1983;36:173-179
© 1983 The Society of Thoracic Surgeons

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Articles

The Efficacy of Postoperative Autotransfusion in Patients Undergoing Cardiac Operations

Surgical Cardiovascular Unit, Massachusetts General Hospital, and the Department of Surgery, Harvard Medical School, Boston, MA

Accepted for publication October 14, 1982.

^* Address reprint requests to Dr. Daggett, Department of Surgery, Massachusetts General Hospital, Boston, MA 02114

	Abstract

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The efficacy of postoperative autotransfusion in lowering the requirement for banked-blood transfusion was studied in two groups, each having 168 patients, who underwent cardiac operations between April, 1979, and May, 1980. A Sorenson autotransfusion system was available for use in the autotransfusion group, whereas the control group received routine closed mediastinal drainage. Of the autotransfusion group, 81% met the criterion for autotransfusion (mediastinal losses of 450 ml or more during 4 hours), but only 61% of the autotransfusion group actually received autologous blood (mean autotransfusion volume, 399 ± 25 ml). The patients receiving autologous blood required significantly less banked blood than their matched controls (447 ± 60 ml and 744 ± 83 ml, respectively; p < 0.001). In the subgroup of patients with large mediastinal losses (more than 1,250 ml), this difference was even greater (autotransfusion, 642 ml compared with control, 1,145 ml;p; < 0.01). Postoperative autotransfusion is a simple, safe, and cost-effective method to reduce dependence on banked blood, especially when mediastinal losses are large. Obtaining maximum benefit requires familiarity of staff with the system and use of a consistent protocol.

	Footnotes

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The authors wish to thank Gail Grant, John Newell, and Christine Waterneaux for their statistical advice and assistance.

	References

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1. Roche JK, Stengle JM. Open-heart surgery and the demand for blood JAMA 1973;225:1516.[Medline]
2. Utley JR, Moores WY, Stephens DB. Blood conservation techniques Ann Thorac Surg 1981;31:482.[Abstract/Free Full Text]
3. Schaff HV, Hauer J, Gardner TJ, et al. Routine use of autotransfusion following cardiac surgery: experience in 700 patients Ann Thorac Surg 1979;27:493.[Abstract/Free Full Text]
4. Thurer RL, Lytle BW, Cosgrove DM, Loop FD. Autotransfusion following cardiac operations: a randomized, prospective study Ann Thorac Surg 1979;27:500.[Abstract/Free Full Text]
5. Dripps RD, Lamont A, Eckenhoff JE. The role of anesthesia in surgical mortality JAMA 1961;178:261.[Medline]
6. Wilson JD, Jaswell HF. Autotransfusion: historical review and preliminary report on a new method Mayo Clin Proc 1968;43:26.[Medline]
7. Zuhdi N, McCullough B, Carey J, Greer A. Double helical reservoir heart-lung machine designed for hypothermic perfusion; primed with 5% glucose in water; inducing hemodilution Arch Surg 1961;82:320.[Medline]
8. Cooley DA, Beall AC, Grondin P. Open heart operations with disposable oxygenator, 5 percent dextrose prime, and normothermia Surgery 1962;52:713.[Medline]
9. Verska JJ, Ludington LG, Brewer LA. A comparative study of cardiopulmonary bypass with blood and nonblood prime Ann Thorac Surg 1974;18:72.[Abstract/Free Full Text]
10. Hardesty RL, Bayer WL, Bahnson HT. A technique for the use of autologous fresh blood during open heart surgery J Thorac Cardiovasc Surg 1968;56:683.[Medline]
11. Wagstaffe JG, Clarke AD, Jackson PW. Reduction of blood loss by restoration of platelet level using fresh autologous blood after cardiopulmonary bypass Thorax 1972;27:410.[Abstract/Free Full Text]
12. Tector AJ, Gabriel RP, Mateicka WA, et al. Reduction of blood usage in open heart surgery Chest 1976;70:454.[Medline]
13. Cohn LH, Fosberg AM, Anderson WP, Collins JJ. The effects of phlebotomy, hemodilution and autologous blood transfusion on systemic oxygenation and whole blood utilization in open heart surgery Chest 1975;68:283.[Medline]
14. Moran JM, Babka R, Silberman S, et al. Immediate centrifugation of oxygenator contents after cardiopulmonary bypass: role in maximum blood conservation J Thorac Cardiovasc Surg 1978;76:510.[Medline]
15. Klebanoff G. Intraoperative autotransfusion with the Bentley ATS-100 Surgery 1978;84:708.[Medline]
16. Noon GP, Solis RT, Natelson EA. A simple method of intraoperative transfusion Surg Gynecol Obstet 1976;143:65.[Medline]
17. Schaff HV, Hauer JM, Bell WR, et al. Autotransfusion of shed mediastinal blood after cardiac surgery J Thorac Cardiovasc Surg 1978;75:632.[Abstract]
18. Kaplan JA, Cannarella C, Jones EL, et al. Autologous blood transfusion during cardiac surgery: a re-evaluation of three methods J Thorac Cardiovasc Surg 1977;74:4.[Abstract]
19. Cordell AR, Lavender SW. An appraisal of blood salvage techniques in vascular and cardiac operations Ann Thorac Surg 1981;31:421.[Abstract/Free Full Text]
20. Symbas PN. Autotransfusion from hemothorax: experimental and clinical studies J Trauma 1972;12:689.[Medline]
21. Cosgrove DM, Thurer RL, Lytle BW, et al. Blood conservation during myocardial revascularization Ann Thorac Surg 1979;28:184.[Abstract/Free Full Text]

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