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Ann Thorac Surg 1980;29:57-62
© 1980 The Society of Thoracic Surgeons

Articles

Comparison of Nonpulsatile and Pulsatile Extracorporeal Circulation on Renal Cortical Blood Flow

James D. Sink, M.D.*, W. Randolph Chitwood, Jr, M.D., Ronald C. Hill, M.D., Andrew S. Wechsler, M.D.

Department of Surgery, Duke University Medical Center and the Durham Veterans Administration Medical Center, Durham, NC

Accepted for publication May 4, 1979.

* Address reprint requests to Dr. Sink, Box 3426, Duke University Medical Center, Durham, NC 27710


   Abstract
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 Abstract
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Radioactive microspheres were used to compare renal cortical blood flow with pulsatile and nonpulsatile extracorporeal perfusion in mongrel dogs. No difference was found in total renal cortical flow or in flow distribution using pulsatile compared with nonpulsatile perfusion when mean perfusion pressure was held constant at a high (80 mm Hg) or low (50 mm Hg) level. Although the present investigation does not resolve the question of whether pulsatile perfusion has advantages over nonpulsatile perfusion in maintaining renal function, the data indicate that any differences between the two techniques must be explained by a mechanism other than increased total cortical blood flow or by redistribution of cortical flow.


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 Abstract
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References
 
Supported in part by Grant 5-R01-HL20226-02 from the National Institutes of Health, and the Medical Research Service of the Veterans Administration.


   References
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 Abstract
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 References
 

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