HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via Google Scholar Google Scholar Search for Related Content Related Collections Related Article

Ann Thorac Surg 1995;60:1591
© 1995 The Society of Thoracic Surgeons

---

Discussion

Discussion

See also page 1583.

DR ALAN G. CASSON (Toronto, Ont, Canada): You are targeting these cells at the RNA level, yet you are looking at the protein product for response. Did you look at the RNA transcript with Northern analysis, for example, to see whether the RNA effect is truly down-regulated at that level?

DR ROBINSON: As yet, we have not examined mRNA levels of the target genes by Northern blot analysis. However, this is important information that we plan to obtain soon to document the sequence-specific effects of our antisense oligodeoxyribonucleotides.

DR CASSON: I enjoyed the paper. It is early work, and I think the last slide summarizes the vast amount of information that we do not yet know.

Related Article

c-myc Antisense Oligodeoxyribonucleotides Inhibit Proliferation of Non-Small Cell Lung Cancer

Lary A. Robinson, Larry J. Smith, Michele P. Fontaine, H. David Kay, Charles P. Mountjoy, and Samuel J. Pirruccello
Ann. Thorac. Surg. 1995 60: 1583-1591. [Abstract] [Full Text]

This Article Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via Google Scholar Google Scholar Search for Related Content Related Collections Related Article