HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Thiagarajan, R. R. Articles by Bratton, S. L. Search for Related Content PubMed Articles by Thiagarajan, R. R. Articles by Bratton, S. L. Related Collections Related Article

---

Correspondence

Reply

^a Children's Hospital Boston, 300 Longwood Ave, Boston, MA 02115
^b Department of Critical Care Medicine, Seattle Children's Hospital, 4800 Sand Point Way NE, Seattle, WA 98105
^c Department of Critical Care Medicine, Primary Children's Medical Center, 100 N Mario Capecchi Dr, Salt Lake City, UT 84113

(Email: ravi.thiagarajan{at}cardio.chboston.org; botcho{at}u.washington.edu; susan.bratton{at}hsc.utah.edu).

To the Editor:

We thank Dr Jung and colleagues [1] for their interest in our article [2]. We agree with their comment that multi-organ failure is an important determinant of mortality in patients supported with extracorporeal membrane oxygenation (ECMO) [1]. However, the primary purpose of our article was to retrospectively report the outcomes and predictors of mortality for adult patients supported with ECMO during cardiopulmonary resuscitation by using data from a multicenter international registry. Given the retrospective nature of our data, information regarding the nature and proximate cause of multi-organ failure and an assessment of end-organ microcirculatory function was not available for analysis. Thus, we are unable to comment on whether assessment of microcirculatory function would have improved outcomes for these patients. The ECMO used to support cardiopulmonary resuscitation aims to provide improved cardiac output during resuscitation and in the post-resuscitation period. Whether the assessment of microcirculatory function during ECMO may help better understand end-organ dysfunction and improve outcomes in these patients may be intriguing and could be studied in the future.

	References

Top References

 

1. Jung C, Figulla HR, Ferrari M. High frequency of organ failures during extracorporeal membrane oxygenation: is the microcirculation the answer? (letter) Ann Thorac Surg 2010;89:345-346.[Free Full Text]
2. Thiagarajan RR, Brogan TV, Scheurer MA, Laussen PC, Rycus PT, Bratton SL. Extracorporeal membrane oxygenation to support cardiopulmonary resuscitation in adults Ann Thorac Surg 2009;87:778-785.[Abstract/Free Full Text]

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Thiagarajan, R. R. Articles by Bratton, S. L. Search for Related Content PubMed Articles by Thiagarajan, R. R. Articles by Bratton, S. L. Related Collections Related Article