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Department of Cardiothoracic Surgery, Stanford University Medical Center, 300 Pasteur Dr, Falk CVRB CV096, Stanford, CA 94305
(Email: ahmadysheikh{at}yahoo.com).
We appreciate the comments put forth by Dr Filsoufi and colleagues [1] regarding our article [2] and agree that magnetic resonance imaging is a useful adjunct to help determine the nature of atrial masses preoperatively.
However, in our case, the pre-test probability of a thrombotic mass was relatively low, as the patient had undergone a primary repair of her atrial septal defect as opposed to patch-based repair, which was the case for the patient described by Filsoufi and colleagues [1], as well as others [3]. Given the rarity of thrombus described after primary repair and asymptomatic profile of the patient, our imaging analyses seemingly confirmed our clinical suspicion of myxoma as opposed to thrombus. If a more rigorous approach of magnetic resonance imaging interpretation had been adopted, such as that proposed by Filsoufi and colleagues [1], it is possible that we would have made the diagnosis preoperatively. However, it is important to stress that clinical management would have remained unchanged.
Nonetheless, the case and subsequent discussion highlights the importance of considering rare causes in the face of a seemingly obvious diagnosis, as well as the utility of validated imaging techniques, such as those described by Filsoufi and colleagues' [1] group to help avoid errors in diagnosis.
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