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Department of Cardiothoracic Surgery, Wake Forest University School of Medicine, Winston-Salem, NC 27157
(Email: tkincaid{at}wfubmc.edu).
We congratulate Dr DOnofrio and his colleagues [1] on their excellent results with the inclusion technique for implantation of stentless porcine valves. We also used this technique early in our series [2], but quickly switched to near universal application of the total root replacement procedure. The primary reason for this switch was to achieve optimal hemodynamics, which has clearly been demonstrated by numerous authors using several types of aortic root prostheses implanted in different manners [3–6]. In addition, a recent long-term analysis of the Freestyle database revealed lower freedom from structural valve degeneration using the inclusion technique compared with subcoronary or total root implantation [7]. One possible anatomic explanation for this finding is that a low-lying, unmobilized right coronary artery can buckle the inflow portion of the prosthesis after anastomosis in the usual location.
Although not observed in DOnofrio and colleagues series, pseudoaneurysm formation has historically been associated with all types of aortic surgery using the inclusion technique, and it remains a concern of ours, especially when constructing anastomoses in the presence of incompletely addressed sinus pathology. The total root procedure thus becomes the most flexible option to manage all forms of aortic root disease.
Do these advantages come at the expense of an increased incidence of coronary ischemia? We believe they do not, as there are certainly documented occurrences of right coronary obstruction, even with traditional stented aortic valve replacements in the absence of any coronary manipulation [8], and these episodes are probably under-detected and under-reported. Right coronary ischemia may easily be confused with other intraoperative and postoperative complications, and similar to so many other problems in medicine, the harder one looks, the more often they are found.
Currently, there is no perfect solution to the management of aortic valve disease, as suggested by the promotion of so many different operations by various surgical groups. Our preferences are based on some scientific evidence, but also on the desire to most closely recreate the anatomy that was bestowed on us by nature.
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