ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Ziad Khabbaz
Christian Latremouille
Jean-Noël Fabiani
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Zegdi, R.
Right arrow Articles by Deloche, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zegdi, R.
Right arrow Articles by Deloche, A.
Related Collections
Right arrow Valve disease

Ann Thorac Surg 2007;84:1043-1044
© 2007 The Society of Thoracic Surgeons


How To Do It

Posterior Leaflet Extension With an Autologous Pericardial Patch in Rheumatic Mitral Insufficiency

Rachid Zegdi, MD, PhDa,b,*, Ziad Khabbaz, MDa,b, Sylvain Chauvaud, MDa,b, Christian Latremouille, MD, PhDa,b, Jean-Noël Fabiani, MDb, Alain Deloche, MDa,b

a Assistance Publique-Hôpitaux de Paris, Service de Chirurgie Cardiovasculaire, Hôpital Européen Georges Pompidou, Paris, France
b Université René Descartes, Paris, France

Accepted for publication December 29, 2006.

* Address correspondence to Dr Zegdi, Hôpital Européen Georges Pompidou, Service de Chirurgie Cardiovasculaire, 20, rue Leblanc, Paris 75908, France (Email: rzegdi{at}hotmail.com).


    Abstract
 Top
 Abstract
 Introduction
 Technique
 Comment
 References
 
We describe our technique of posterior leaflet extension with an autologous pericardial patch in patients suffering from rheumatic mitral regurgitation. Several simple rules have allowed us to achieve satisfying long-term results.


    Introduction
 Top
 Abstract
 Introduction
 Technique
 Comment
 References
 
Although the occurrence of rheumatic mitral valve disease is nowadays exceptional in developed countries, with sporadic cases discovered in elderly patients, it is still a major concern in developing countries, where considerable numbers of pediatric cases are being diagnosed each year.

The mainstay of the surgical repair technique relies on posterior leaflet extension using an autologous pericardial patch [1]. Several technical hints resulting from more than 30 years of experience in our department are presented.


    Technique
 Top
 Abstract
 Introduction
 Technique
 Comment
 References
 
After performing a median sternotomy, cardiopulmonary bypass is established between the two vena cava and the ascending aorta. The aorta is cross-clamped and the heart arrested using cardioplegia according to one’s method. The left atrium is then opened, classically in the interatrial groove, and the mitral valve exposed.

The mitral valve is carefully inspected and the mechanisms of mitral regurgitation identified as previously reported [2]. Commissural fusioning should also be looked for. The decision to repair the mitral valve relies on the evaluation of the anterior leaflet pliability, depending on the extent of leaflet fibrosis or calcification. If leaflet fibrosis or calcification is extensive, then repair is likely to fail or to end up with significant mitral stenosis. A simple and effective technique to rapidly evaluate this is by pushing with a forceps the anterior mitral valve toward the left ventricle. If the anterior leaflet returns directly into position with a "reboundlike" effect, then fibrosis is too extensive. If it stays easily in place, then leaflet pliability is generally sufficient to perform repair, and we should move on to the next step.

Commissurotomy, when necessary, is first performed. Retraction of the posterior leaflet is usually very marked, and its height often reduced to no more than a few millimeters. The posterior leaflet is detached along the annulus. This incision should be extended as far as possible toward both commissures. Then the subvalvular apparatus is examined, and retracted secondary chordae should be excised. That would confer more mobility to the free margin of the extended leaflet.

An autologuous pericardial patch that has previously been pretreated with a 0.625% glutaraldehyde-buffered solution should then be tailored. The glutaraldehyde solution makes the pericardium stiffer, rendering it easier to handle. The length of the oval patch should correspond to the intercommissural distance (Fig 1). One should not hesitate to keep a height of at least 3 cm when tailoring the patch. After the loss of tissue due to the suture lines, there should remain enough tissue in place to allow the pericardium to bulge and move anteriorly during systole toward the anterior leaflet (Fig 2). The bulk of the pericardium would form the body of the posterior valve that would serve as an "abutment" to which the anterior leaflet would coapt during systole. The extremities of the patch should also be cut round and not sharp, to confer a greater height in the commissural region.


Figure 1
View larger version (40K):
[in this window]
[in a new window]

 
Fig 1. Schematic representation of posterior leaflet extension with an autologous pericardial patch (gray area).

 

Figure 2
View larger version (86K):
[in this window]
[in a new window]

 
Fig 2. Final aspect of posterior leaflet extension with an autologous pericardial patch. Redundancy of the patch allows anterior displacement of the coaptation surface between the two mitral leaflets.

 
Suturing of the patch is done using two or three running sutures with a 4-0 nonabsorbable monofilament. Care should be taken not to leave too much space between sutures along the annulus suturing of the patch. Any residual leak at that level may lead to a more or less severe hemolysis, the regurgitant jet hitting the prosthetic ring.

The final step is inserting a prosthetic mitral annulus. The sizing is critical. According to Carpentier’s techniques, the choice of the ring relies on the measurement of the surface of the anterior leaflet [2]. In cases of rheumatic mitral regurgitation, however, an important pericardial extension of the posterior leaflet allows an oversizing (usually one size) of the prosthetic ring [1]. This oversizing has also the potential to prevent significant residual mitral stenosis, particularly when the anterior leaflet is small and mildly fibrotic.


    Comment
 Top
 Abstract
 Introduction
 Technique
 Comment
 References
 
The mechanism of mitral regurgitation in rheumatic disease is usually multifactorial. The most frequent mechanism is posterior leaflet retraction (type III in Carpentier’s functional classification [2]) occurring in almost 60% of cases [3]. That is primarily due to progressive fibrosis of the leaflet and subvalvular apparatus and is frequently associated with prolapse of the anterior leaflet (type II) resulting from marginal chordae or papillary muscles elongation. Mitral stenosis is common (39% in the series of Chauvaud and colleagues [3]), secondary to commissural fusioning or leaflet rigidity.

Mitral valve repair in rheumatic valve disease has been shown to give suboptimal but satisfying long-term results, with 82% freedom from reoperation at 10 years, and a considerably lower rate of thromboembolic events when compared with prosthetic mitral valve replacement [3]. That is particularly important in children and in women of child-bearing age.

Following these surgical rules, satisfying long-term results have been achieved (2% reoperation per year) in our department. A large posterior leaflet extension is critical in achieving these good results. We have never seen any systolic anterior motion of the anterior leaflet after repair of a rheumatic mitral insufficiency. That is explained by the fact that the anterior leaflet is usually short, with a pliability that is less than normal. Oversizing of the prosthetic ring also helps preventing systolic anterior motion.

Pericardial extension of the anterior leaflet provides better results than prosthetic annuloplasty alone in rheumatic mitral regurgitation [4]. However, there is still a controversy regarding the type (anterior or posterior) of the pericardial extension to perform. Although both techniques are easy to do, very long term satisfying results (20 years) have only been reported with the posterior pericardial extension [3]. Cuspal thinning is another way of extending the posterior leaflet. Although others have reported good long-term results [5], we abandoned it a long time ago as the technique is more challenging, and the resulting leaflet extension is usually modest.


    References
 Top
 Abstract
 Introduction
 Technique
 Comment
 References
 

  1. Chauvaud S, Jebara V, Chachques JC, et al. Valve extension with glutaraldehyde-preserved autologous pericardiumResults in mitral valve repair. J Thorac Cardiovasc Surg 1991;102:171-177discussion 177–8.[Abstract]
  2. Carpentier A. Cardiac valve surgery: the "French correction." J Thorac Cardiovasc Surg 1983;86:323-337.[Medline]
  3. Chauvaud S, Fuzellier JF, Berrebi A, Deloche A, Fabiani JN, Carpentier A. Long-term (29 years) results of reconstructive surgery in rheumatic mitral valve insufficiency Circulation 2001;104(Suppl 1):I12-I15.[Medline]
  4. Acar C, Saez de Ibarra J, Lansac E. Widening plasty of the anterior cusp in rheumatic mitral insufficiency Arch Mal Coeur 2004;97:875-880(in French).[Medline]
  5. Kumar AS, Talwar S, Saxena A, Singh R, Velayoudam D. Results of mitral valve repair in rheumatic mitral regurgitation Interact Cardiovasc Thorac Surg 2006;5:356-361.[Abstract/Free Full Text]



This article has been cited by other articles:


Home page
Ann. Thorac. Surg.Home page
A. M. Calafiore, I. Farah, A. L. Iaco, S. Al Ahmari, H. Al Amri, and M. Di Mauro
Posterior Chordal Cutting in Rheumatic Mitral Regurgitation Due to Hypomobility of the Posterior Leaflet
Ann. Thorac. Surg., October 1, 2011; 92(4): 1532 - 1533.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
M. A. Daneshmand, C. A. Milano, J. S. Rankin, E. F. Honeycutt, L. K. Shaw, R. D. Davis, W. G. Wolfe, D. D. Glower, and P. K. Smith
Influence of Patient Age on Procedural Selection in Mitral Valve Surgery
Ann. Thorac. Surg., November 1, 2010; 90(5): 1479 - 1486.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
M. A. Daneshmand, C. A. Milano, J. S. Rankin, E. F. Honeycutt, M. Swaminathan, L. K. Shaw, P. K. Smith, and D. D. Glower
Mitral Valve Repair for Degenerative Disease: A 20-Year Experience
Ann. Thorac. Surg., December 1, 2009; 88(6): 1828 - 1837.
[Abstract] [Full Text] [PDF]


This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Ziad Khabbaz
Christian Latremouille
Jean-Noël Fabiani
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Zegdi, R.
Right arrow Articles by Deloche, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zegdi, R.
Right arrow Articles by Deloche, A.
Related Collections
Right arrow Valve disease


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS