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Ann Thorac Surg 2002;73:2036
© 2002 The Society of Thoracic Surgeons
a Department of Cardiovascular Surgery, Trakya University Medical Faculty, 22030 Edirne, Turkey
e-mail: hasansunar{at}trakya.edu.tr
To the Editor
We read with interest the article by Kele
and colleagues on the treatment of Brucella endocarditis [1]. We agree with the authors that medical therapy alone is not sufficient in treating brucella endocarditis and best results are achieved by combining antimicrobial and surgical therapy. They report patients with complicated valvular lesions such as perforation or abscess that required valvular replacement with good results. Brucella endocarditis involves predominantly the aortic valve, and embolic phenomena are common features in addition to valve destruction and perivalvular abscess formation [2]. Valve replacement is usually preferred, however, in a small number of patients with endocarditis due to other microorganisms, simple excision of the vegetation "vegetectomy" has been reported as a conservative approach [3], if the valve is not destroyed or if there is no root abscess.
We reported a vegetectomy operation in a 19-year-old man with brucella endocarditis [4]. In our patient, the diagnosis of brucellosis was established serologically. He had a positive Wrights tube agglutination test with a titer of 1/640 and a positive 2-mercaptoethanol test with a titer of 1/160. Transthoracic echocardiography revealed moderate aortic regurgitation and a vegetation 1 cm in diameter on the aortic valve. Four weeks after specific antimicrobial treatment (doxycycline, rifampicin, and trimethoprim plus sulfamethoxazole), surgical exploration revealed a single vegetation on an otherwise normal aortic valve. The aortic valve was competent after excision of vegetation. Antimicrobial therapy was continued for 9 months. Mild aortic regurgitation with no vegetation was detected after 2 years by echocardiography. Early operations combined with antimicrobial therapy before abscess formation and perforation of valve may save the native valve.
References
C., Bozbu
a N.,
i
mano
lu M., Güler M., Erdo
an H.B., Akinci E., Yakut C. Surgical treatment of Brucella endocarditis. Ann Thorac Surg 2001;71:1160-1163.Related Articles
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