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Ann Thorac Surg 2002;73:S367
© 2002 The Society of Thoracic Surgeons


SUPPLEMENT: OUTCOMES 2001: SCIENTIFIC ABSTRACTS

The effect of neuropsychological deficits on quality of life 6 months after cardiac surgery

M.J. Andrew, BA, (Hons)a, R.A. Baker, PhDa, J.L. Knight, FRACSa

a Cardiac Surgery Research, Flinders Medical Centre, Adelaide, South Australia, Australia

Introduction. The impact of postoperative neuropsychological (NP) deficits on quality of life (QOL) after cardiac surgery is not well understood. The aim of this investigation was to determine the relationship between NP deficits and QOL 6 months after cardiac surgery.

Methods. With informed consent and institutional approval, 77 patients undergoing cardiac surgery were administered a NP battery preoperatively, before discharge, and 6 months postoperatively. NP deficits were defined using reliable change criteria. QOL was assessed preoperatively and 6 months postoperatively using standardized instruments (SF-36, Depression Anxiety Stress Scale [DASS], and Beck Depression Inventory [BDI]).

Results. Approximately 10% of patients exhibited deficits on at least two NP measures 6 months postoperatively. Significant improvement at 6-month follow-up was evident on all QOL measures. After controlling for preoperative QOL scores, 6-month NP deficits correlated significantly with 6-month SF-36 measures of general health, physical, physical role, and social functioning, DASS anxiety, and BDI depression. NP deficits were a significant multivariate predictor of 6-month physical functioning (p = 0.005), physical role functioning (p = 0.038), and DASS anxiety (p = 0.04). Other significant multivariate predictors of 6-month QOL included preoperative QOL scores, perioperative myocardial infarction, and length of stay.

Conclusions. NP deficits detected 6 months after cardiac surgery have a negative impact on QOL. These results highlight the importance of presurgical assessments of QOL in this population.





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