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Ann Thorac Surg 1998;66:1451
© 1998 The Society of Thoracic Surgeons


Update

Invited commentary

John R. Benfield, MDa

a Division of Cardiothoracic Surgery, University of California, Davis, 4301 X St, Suite 2250, Sacramento, CA 95817-2214, USA

Invited commentary

Doctor Dyke is probably correct that "... the seeming contrast between experimental and clinical data may lie in the varying degrees of myocardial injury." With the experimental data in favor of using triiodothyronine so strong, why not develop a cooperative trial into which many patients could be entered in a relatively short period of time? With standardized entry and evaluation criteria, and administration of triiodothyronine or pla-cebo by random choice, the clinical waters might become less murky.





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