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Ann Thorac Surg 1997;64:1528
© 1997 The Society of Thoracic Surgeons
Victorian Paediatric Cardiac Surgical Unit, Royal Children's Hospital, Flemington Rd, Melbourne, 3052, Australia.
To the Editor:
It was with much interest that we reviewed the recent article by Pedersen and associates [1]. However, there are some important points that we think need to be clarified. Their team used three inlet pressure conditions for this study: 0, -50, and -100 mm Hg. In our center, we have performed more than 100 extracorporeal membrane oxygenations in the last 10 years using the Biomedicus (Eden Prairie, MN) centrifugal pump exclusively (after initially trying roller pumps). In practice we never encounter such negative (ie, subatmospheric) inlet pressures. Typically, the monitored patient will show inlet pressures in the range of -20 to 0 mm Hg. Sometimes, the pressure becomes greater than 0, depending on the circulating blood volume. If the pressure becomes less than -20 mm Hg, the flow will decrease (causing an alarm to sound), requiring the patient's nurse to administer fluid. In an extreme case, a venous cannula may require repositioning. It is a mistake to think that only a constrained vortex (centrifugal) pump will produce a negative inlet pressure. This same study could have been undertaken with a roller pump, which can produce either positive or negative pressure, limited only by servo-regulation (if used) or circuit disruption. Servo-regulation of the Biomedicus pump appears to be a useful and effective way to monitor and control inlet pressure. As long as retrograde flow cannot occur when the pump head slows or stops, this is a great idea, and enhances the usefulness of the centrifugal pump in pediatric extracorporeal membrane oxygenation.
Reference
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