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Department of Cardiothoracic Surgery, The University of Iowa Hospitals & Clinics, Room SE 532, 200 Hawkins Dr, Iowa City, IA 52242-1062
(Email: wayne-richenbacher@uiowa.edu).
| The first 20% of the full text of this article appears below. |
Lutter and colleagues [1] report the percutaneous implantation of tissue-engineered pulmonary valve stents in three juvenile sheep. In their experimental model, they used size-matched, decellularized, porcine pulmonary valves that were fixed to a nitinol stent. The valves were serially seeded with autologous myofibroblasts and endothelial cells. The seeded valve stents were deployed percutaneously at the level of the native pulmonary valve. Angiographic and echocardiographic follow-up to 4 weeks demonstrated no pulmonary insufficiency.
Related Article
Ann. Thorac. Surg. 2010 89: 259-263.
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