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Ann Thorac Surg 2008;86:848. doi:10.1016/j.athoracsur.2008.05.054
© 2008 The Society of Thoracic Surgeons
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Patricia A. Thistlethwaite
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Original Articles: Adult Cardiac

Invited Commentary

Patricia A. Thistlethwaite, MD, PhD

Division of Cardiothoracic Surgery, University of California, San Diego, 200 West Arbor Dr, San Diego, CA 92103-8892

(Email: pthistlethwaite@ucsd.edu).

The first 20% of the full text of this article appears below.

The study of the molecular causes of human disease is coming to the forefront of medicine since the sequencing of the human genome and the development of proteomic research. In the field of neurocognitive decline, the apolipoprotein E {epsilon}4 (APOE {epsilon}4) allele has been associated with the development of Alzheimer's disease, C-reactive protein (CRP) polymorphisms have been linked to an increased risk of stroke, and the release of S100 protein and specific S100 polymorphisms have been correlated with the development of ischemic . . . [Full Text of this Article]


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The Apolipoprotein E {epsilon}4 Allele is not Associated With Cognitive Dysfunction in Cardiac Surgery
Brendan S. Silbert, Lisbeth A. Evered, David A. Scott, and Tiffany F. Cowie
Ann. Thorac. Surg. 2008 86: 841-847. [Abstract] [Full Text] [PDF]





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