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Ann Thorac Surg 2008;86:541-542. doi:10.1016/j.athoracsur.2008.04.035
© 2008 The Society of Thoracic Surgeons
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Original Articles: Adult Cardiac

Invited Commentary

Michael E. Jessen, MD

Department of Cardiovascular & Thoracic Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-8879

(Email: michael.jessen@utsouthwestern.edu).

The inflammatory response to cardiopulmonary bypass (CPB) has been studied extensively, yet it remains incompletely understood. Multiple investigations have established that blood contact with foreign surfaces of the circuit components and with nonendothelialized surfaces in the surgical field contributes to this inflammatory process and ultimately affects patient morbidity and mortality. In this study Fabre and colleagues [1] collected blood samples during cardiac surgery in a manner designed to isolate the effects on blood that is lost from the heart and contacts the pericardial cavity before it is returned to the CPB circuit from the . . . [Full Text of this Article]


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Ann. Thorac. Surg. 2008 86: 537-541. [Abstract] [Full Text] [PDF]





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