Ann Thorac Surg 2008;85:2099. doi:10.1016/j.athoracsur.2008.03.022
© 2008 The Society of Thoracic Surgeons
Original Articles: Pediatric Cardiac
Invited Commentary
Richard W. Kim, MD
Surgery, Section of Cardiac Surgery, Yale University School of Medicine, 333 Cedar St, 121 FMB, New Haven, CT 06520-8039
(Email: richard.w.kim@yale.edu).
| The first 20% of the full text of this article appears below. |
In demonstrating the need for endocardial BMP receptor 1a (BMPR1a) expression in atrioventricular (AV) valve development, Kaneko and colleagues [1] confirm important, previously defined work that identified the importance of BMP signaling in endocardial cushion defects and AV valve formation [2, 3]. Significantly, they not only further identify potential downstream molecular targets of BMPR1a signaling in the embryonic heart, . . . [Full Text of this Article]
Copyright © 2008 by The Society of Thoracic Surgeons.