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Ann Thorac Surg 2008;85:458-459. doi:10.1016/j.athoracsur.2007.09.051
© 2008 The Society of Thoracic Surgeons
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Xu Yu Jin
Ravi Pillai
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Original Articles: Cardiovascular

Invited Commentary

Xu Yu Jin, MD, PhD, Ravi Pillai, FRCS

Department of Cardiothoracic Surgery, John Radcliffe Hospital, Oxford, OX3 9DU United Kingdom

(Email: xy.jin@orh.nhs.uk).

The first 20% of the full text of this article appears below.

To translate compelling science into patient benefits is always a challenging process in modern medicine. The development of effective protection of the hypertrophic hearts during aortic valve replacement (AVR) has been just one of the examples. Although the cardioplegia regime, delivery route, and temperature have reached a general consensus, the clinical benefits of adding "hot shot" at the end of the AVR procedure remain an ongoing debate. The benefits of hot shot to metabolic recovery had been reported during coronary artery bypass surgery [1]. However, the randomized clinical trials reported by Edwards and colleagues [2] and by Falcoz and colleagues [3] in the AVR setting were unable to detect significant differences in cardiac enzyme release early after surgery, when the terminal hot shot was added by antegrade . . . [Full Text of this Article]






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Copyright © 2008 by The Society of Thoracic Surgeons.