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a Department of Pathology and Molecular Medicine, McMaster University, 120 Main St West, Hamilton, Ontario, LBN 3Z5 Canada
b Department of Medicine, McMaster University, 120 Main St West, Hamilton, Ontario, LBN 3Z5 Canada
c Department of Anesthesia, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, Berlin, D-13353 Germany
(Email: twarken@mcmaster.ca; crowthrm@mcmaster.ca; koster@dhzb.dc).
| The first 20% of the full text of this article appears below. |
To the Editor:
| Dr Warkentin discloses that he has a financial relationship with The Medicines Company.
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We thank Barzaghi and colleagues [1], for responding to the article of Koster and colleagues [2] reporting on an observational study of patients with immune heparin-induced thrombocytopenia (HIT) in association with use of a ventricular assist device (VAD), and to the accompanying editorial [3] addressing the difficulties of accurate laboratory diagnosis of HIT in this patient population. Barzaghi and colleagues [1] point out that the more diagnostically specific platelet activation assays (eg, serotonin-release assay) are not widely available; therefore, "in [the] presence of
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