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Ann Thorac Surg 2007;84:840
© 2007 The Society of Thoracic Surgeons


Original Articles: Cardiovascular

Invited commentary

Alan F. Merry, MB ChB, FANZCA

Department of Anesthesiology, University of Auckland, Private Bag 92019, Auckland, New Zealand 1003

(Email: a.merry@auckland.ac.nz).

The first 20% of the full text of this article appears below.

This study [1] adds to the confidence clinicians can have in the direct thrombin inhibitor bivalirudin as an anticoagulant for off-pump coronary artery bypass (OPCAB) surgery when heparin is contraindicated. Anticoagulation for cardiac surgery in patients with heparin-induced thrombocytopenia (HIT) or thrombotic syndrome (TS) is particularly difficult. It is becoming increasingly apparent that the direct thrombin inhibitor bivalirudin has considerable merit as an alternative to heparin in this situation. However . . . [Full Text of this Article]







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