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Ann Thorac Surg 2007;84:573
© 2007 The Society of Thoracic Surgeons
Cardiac Surgery Group, Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Groby Rd, Leicester, LE3 9QP United Kingdom
(Email: mg50@le.ac.uk).
| The first 20% of the full text of this article appears below. |
Patients with severe diffuse coronary artery disease and refractory angina who can not be treated with conventional coronary artery bypass graft surgery or angioplasty represent a clinical challenge due to the absence of proven effective alternative treatments. Therapies such as transmyocardial laser and cardiac denervation have not had the expected results, and our own group demonstrated that although these two treatment modalities can induce angina relief in the short-term, their efficacy was limited (eg, most patients remained with some degree of angina) and their efficacy was also transient (eg, the benefit was partly lost by 42-month follow-up), and this is not associated with detectable improvement in myocardial perfusion as assessed by magnetic resonance imaging [1]. Our
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Ann. Thorac. Surg. 2007 84: 568-573.
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