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Ann Thorac Surg 2007;84:49-50
© 2007 The Society of Thoracic Surgeons

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Original Articles: Cardiovascular

Invited commentary

Louisiana Cardiovascular and Thoracic Institute, 211 4th St, Alexandria, LA 71301

(Email: cable_david@suddenlink.net).

The first 20% of the full text of this article appears below.

Technologic advances of the last 2 decades have had little impact on saphenous vein graft disease. Graft failure is multifactorial, but outside of immediate technical deficiencies, current research suggests serial progression from neointimal hyperplasia to atherosclerosis. The organ culture model is well established, and we demonstrated that human radial and internal mammary arteries and saphenous veins reacted similarly to clinical observations [1]. A vast amount of literature supports this model.

A threshold was witnessed lately with the advent of drug-eluting stents. With the recent controversy in stent therapy, surgical revascularization . . . [Full Text of this Article]

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