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Ann Thorac Surg 2007;83:654
© 2007 The Society of Thoracic Surgeons
Department of Cardiovascular Surgery, Medical University Berlin, Luisenstrasse 13, Berlin, D-10117 Germany
(Email: pascal.dohmen@charite.de).
| The first 20% of the full text of this article appears below. |
Todays treatment of complex congenital cardiovascular defects of the right ventricular outflow tract, such as hypoplastic, stenotic right ventricular outflow tract, or the pulmonary artery in tetralogy of Fallot, are far from optimal as generally nonviable patch materials are used. This results in repeated surgical intervention for two reasons. First, the patch reconstruction and the absence of a functional pulmonary valve will lead to right ventricular failure, increased tricuspid valve regurgitation, and ventricular arrhythmias. Second, material degeneration will result in obstructive pannus overgrowth and calcification after implantation.
Tissue engineering
Related Article
Ann. Thorac. Surg. 2007 83: 648-654.
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