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Ann Thorac Surg 2006;82:2030
© 2006 The Society of Thoracic Surgeons
Department of Surgery, Robert-Bosch-Krankenhaus, Auerbachstrasse 110, Stuttgart, 70376 Germany
(Email: twalles@yahoo.com).
| The first 20% of the full text of this article appears below. |
The concept of isolated lung perfusion to increase the effective chemotherapeutic dose in the target tumor tissue by avoiding systemic side effects has been intensively investigated and has already been clinically applied. Retrograde lung perfusion by cannulating the pulmonary veins is a rather new experimental approach. It is hypothesized that a more homogenous drug distribution in the lung tissue can be attained by retrograde perfusion of the pulmonary artery and the bronchial artery vascular tree. In their article, Krueger and colleagues [1] tested the hypothesis of whether
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