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Ann Thorac Surg 2006;82:1418-1419
© 2006 The Society of Thoracic Surgeons
Division of Cardiothoracic Surgery, University of North Carolina at Chapel Hill, 3040 Burnett Womack, CB 7065, Chapel Hill, NC 27599
(Email: selzman@med.unc.edu).
| The first 20% of the full text of this article appears below. |
The Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (REMATCH) trial investigating lifetime use of left ventricular assist devices (LVAD) in non-transplant-eligible patients with end-stage heart disease was performed between 1998 and 2001 using the HeartMate vented electric (VE) device (Thoratec Corp, Pleasanton, CA). This seminal study rigorously and prospectively established new standards for survival, quality of life, and adverse events in this severely ill patient population.
Despite the favorable results for LVAD versus optimal medical management, REMATCH is often criticized by the medical community: few patients survived more than 2 years secondary to high rates of adverse events (infection, bleeding, neurologic) and device failure (35% at 2 years). As
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