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Ann Thorac Surg 2006;82:1204
© 2006 The Society of Thoracic Surgeons

Original Articles: General Thoracic

Invited commentary

Douglas E. Paull, MDa,d, Katherine Heminger, MSb,c,d, Steven J. Berberich, PhDb,c,d

a Department of Surgery, VA Medical Center, 4100 W Third St, No. 112, Dayton, OH 45428
b Department of Biochemistry and Molecular Biology, VA Medical Center, 4100 W Third St, No. 112, Dayton, OH 45428
c The Center for Genomics Research, Boonshoft School of Medicine, VA Medical Center, 4100 W Third St, No. 112, Dayton, OH 45428
d Wright State University School of Medicine, VA Medical Center, 4100 W Third St, No. 112, Dayton, OH 45428

(Email: douglas.paull@wright.edu).

The first 20% of the full text of this article appears below.

Tsubochi and colleagues [1] present further evidence that molecular markers, in this case cyclooxyenase-2 (COX-2) expression, are useful in the determination of prognosis after resection of non-small cell lung cancer (NSCLC) [1]. In their retrospective study of 219 patients, utilizing immunohistochemical staining of surgical specimens, patients with tumor expression of COX-2 had a worse prognosis. This effect was valid in four patient subgroups: . . . [Full Text of this Article]


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Ann. Thorac. Surg. 2006 82: 1198-1204. [Abstract] [Full Text] [PDF]





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