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Ann Thorac Surg 2005;80:243-244
© 2005 The Society of Thoracic Surgeons

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Original article: Cardiovascular

Invited commentary

Division of Cardiothoracic Surgery, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555-0528

(Email: mkurusz@utmb.edu).

The first 20% of the full text of this article appears below.

	Introduction

 
Minimizing blood damage during cardiopulmonary bypass (CPB) and its sequelae, such as the systemic inflammatory response (SIR), has been an ongoing quest for decades. Recent efforts have focused on reducing the CPB blood surface area and concomitant hemodilution. In this article, a large number of patients undergoing first-time coronary artery bypass surgery had a modified, low-prime CPB circuit. To achieve reduced surface area, the circuit had no venous or cardiotomy reservoir, roller pump and heat exchanger/bubble trap for cardioplegia delivery, or arterial line filter. Venous drainage was achieved by direct aspiration using a centrifugal pump integral to the inlet of the oxygenator. During CPB, all cardiotomy-suctioned blood was processed by a cell salvage system. To address possible entrainment of room air at the venous cannulation site, . . . [Full Text of this Article]