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Ann Thorac Surg 2005;80:161-162
© 2005 The Society of Thoracic Surgeons
Division of Cardiothoracic Surgery, Jackson Memorial Hospital, University of Miami, 1611 NW 12th Ave, East Tower 3072 (R-114), Miami, FL 33136
(Email: tsalerno@med.miami.edu).
| The first 20% of the full text of this article appears below. |
de Zeeuw and colleagues [1] have developed an elegant and technically challenging model to evaluate myocardial perfusion after creation of a left ventricular-to-coronary artery shunt (LV-CA). This animal model specifically assesses transmyocardial blood flow and coronary physiology in a normal porcine heart without collateral circulation. This is a physiologic state that is uncommon in patients with chronic arterial occlusive disease. However, it may represent a plausible intervention in the treatment of patients with coronary artery disease.
A valveless LV-CA bypass has a significant impact on regional myocardial perfusion. The conduit used in this study reverses mid-left anterior descending coronary artery (LAD)
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