Ann Thorac Surg 2005;79:989
© 2005 The Society of Thoracic Surgeons
INVITED COMMENTARY
Paul De Leyn, MD, PhD
Leuven Lung Cancer Group, Department of Thoracic Surgery, University Hospital Gasthuisberg, Catholic University, Herestraat 49, B-3000 Leuven, Belgium
(E-mail: paul.deleyn@uz.kuleuven.ac.be).
| The first 20% of the full text of this article appears below. |
A solitary pulmonary nodule remains a diagnostic challenge in daily practice. Positron emission tomography (PET) with 18F-2-fluoro-2-deoxy-glucose (FDG) has been studied extensively in the evaluation of the indeterminate pulmonary nodule. As shown by a large meta-analysis, the sensitivity to detect malignancy is 96.8% with a specificity of 77.8% [1]. Potential pitfalls in sensitivity are due to the fact that a critical mass of metabolically active malignant cells is required for PET diagnosis. It is well-known that false negative findings occur in lesions less than 1 cm. Due to these good results obtained with PET . . . [Full Text of this Article]
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Copyright © 2005 by The Society of Thoracic Surgeons.