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Ann Thorac Surg 2004;78:1337-1338
© 2004 The Society of Thoracic Surgeons

INVITED COMMENTARY

Madhav Swaminathan, MD

Division of Cardiothoracic Anesthesia and Critical Care Medicine, Department of Anesthesiology, Box 3094, Duke University Medical Center, Durham, NC 27710, USA

swami001@mc.duke.edu

The first 20% of the full text of this article appears below.

Ranucci and associates report a multicenter, prospective cohort study of fenoldopam prophylaxis in cardiac surgical patients at high risk for postoperative acute renal failure (ARF). Fenoldopam was administered in 108 patients prospectively, and data were analyzed against a matched retrospective cohort of 108 control group patients who did not receive the drug. The authors found a significant reduction in incidence of ARF with fenoldopam use, but could not confirm this in a multivariable analysis. However, fenoldopam was found to be an independent renal protective factor in a subgroup of 70 patients with low cardiac output syndrome.

Several . . . [Full Text of this Article]


Related Article

Fenoldopam Prophylaxis of Postoperative Acute Renal Failure in High-Risk Cardiac Surgery Patients
Marco Ranucci, Giorgio Soro, Nicoletta Barzaghi, Alessandro Locatelli, Gianbeppe Giordano, Angelo Vavassori, Aldo Manzato, Chiara Melchiorri, Tiziana Bove, Glauco Juliano, and Maria Francesca Uslenghi
Ann. Thorac. Surg. 2004 78: 1332-1337. [Abstract] [Full Text] [PDF]





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