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Ann Thorac Surg 2002;74:24
© 2002 The Society of Thoracic Surgeons


Original article: cardiovascular

Invited commentary

David K.C. Cooper, MDa

a Transplantation Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA

The first 20% of the full text of this article appears below.


    Introduction
 
In this very interesting paper from Dr Ray Chiu’s group, Saito and colleagues report that intravenously-injected mouse bone marrow stromal cells successfully engrafted into the bone marrow of rats in the absence of any immunosuppressive therapy. Furthermore, following ligation of one of the rat’s coronary arteries, mouse cells could be detected in the infarcted myocardium. In similarly treated rats that had not undergone coronary ligation, mouse cells could not be identified in the heart. The . . . [Full Text of this Article]


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Xenotransplant cardiac chimera: immune tolerance of adult stem cells
Takayuki Saito, Jin-Qiang Kuang, Bindu Bittira, Abdulaziz Al-Khaldi, and Ray C.-J. Chiu
Ann. Thorac. Surg. 2002 74: 19-24. [Abstract] [Full Text] [PDF]






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