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Ann Thorac Surg 2002;73:824
© 2002 The Society of Thoracic Surgeons

Invited commentary

^a Cardiac Physiology Laboratory, Divisions of Circulatory Physiology and Cardiology, Columbia University, 650 W 168th St, New York, NY 10032, USA

In this article, Dr Liu and colleagues demonstrate the vasodilating effects of vascular endothelial growth factor (VEGF, also known as vascular permeability factor) on isolated internal mammary artery vascular rings. It is further demonstrated that this relaxation is endothelium-dependent and is mediated by nitric oxide (NO). This study reports important confirmatory data of prior studies. Vasodilatory actions of VEGF have been demonstrated previously in animal and human endothelium and this has been demonstrated to be dependent upon NO release . . . [Full Text of this Article]

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Vascular endothelial growth factor-mediated, endothelium-dependent relaxation in human internal mammary artery

Ming-Hui Liu, Hongkui Jin, H. Storm Floten, Zhev Ren, Anthony P.C. Yim, and Guo-Wei He
Ann. Thorac. Surg. 2002 73: 819-824. [Abstract] [Full Text] [PDF]