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Ann Thorac Surg 2002;73:587
© 2002 The Society of Thoracic Surgeons

Invited commentary

Clyde Saldanha, MB, MDa

a London, England, United Kingdom

e-mail: csaldanha@aol.com

A number of studies have demonstrated that glucose-insulin-potassium (GIK) solutions are beneficial in patients undergoing cardiac surgery. The mechanism by which they exert their beneficial effect, however, is not fully understood. In this study it was demonstrated that in diabetic sheep GIK improves left ventricular contractility and ventriculoarterial coupling, and decreases total mechanical work, without significantly affecting stroke work. This improvement in stroke work efficiency is a novel finding, and the authors postulate that it may . . . [Full Text of this Article]


Related Article

Glucose-insulin-potassium solution improves left ventricular mechanics in diabetes
Tharumenthiran Ramanathan, Kazuaki Shirota, Shin Morita, Takashi Nishimura, Yifei Huang, and Stephen N. Hunyor
Ann. Thorac. Surg. 2002 73: 582-587. [Abstract] [Full Text] [PDF]





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