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Ann Thorac Surg 2002;73:129-130
© 2002 The Society of Thoracic Surgeons

Invited commentary

^a Department of Cardiovascular Surgery, Hôpital Bichat, 46 rue Henri-Huchard, 75018 Paris, France

e-mail: ccv-bloc.sec3@bch.ap-hop-paris.fr

The growing development of off-pump coronary artery bypass surgery has generated a rekindled interest in the means of reducing the invasiveness of cardiopulmonary bypass (CPB) and, more specifically, the adverse events related to the generalized inflammatory response triggered by extracorporeal circulation. This response results from the complex interplay of multiple cascades among which a pivotal role is played by neutrophil activation. However, whereas most studies have focused on the magnitude or the intraoperative time course of neutrophil activation, few have addressed the issue of the delayed effects of this phenomenon. The study by Dr Chello . . . [Full Text of this Article]

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