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Ann Thorac Surg 2001;72:843-844
© 2001 The Society of Thoracic Surgeons
a Human Physiology, University of CaliforniaDavis, 4147A Tupper Hall, Davis, CA 95616, USA
e-mail: seanderson@ucdavis.edu
This paper is one of numerous recently published which underscores our incomplete understanding of the roles of Na and the Na/H exchanger (NHE1) in myocardial injury induced by ischemia/reperfusion. The hypothesis tested here arises from ample evidence that untreated ischemia leads to increases in cytosolic H, Na, and Ca concentrations with the first two ions linked by NHE1 and the latter two by sarcolemmal Na/Ca exchange. There is also ample evidence that in
Related Article
Ann. Thorac. Surg. 2001 72: 836-843.
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