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Ann Thorac Surg 2001;72:534
© 2001 The Society of Thoracic Surgeons

Invited commentary

William L. Holman, MDa

a Department of Cardiothoracic Surgery, University of Alabama at Birmingham, 1530 3rd Ave South – 2RB719, Birmingham, AL 35294-0007, USA

e-mail: wholman@its.uab.edu

Wilkes and associates performed a meta-analysis of randomized trials that compared the use of albumin and hydroxyethyl starch (HES) solutions in cardiac surgery. Their goal was to determine if the use of HES solutions is associated with increased postoperative blood loss. The rationale for performing this meta-analysis is the adverse effect that HES solutions have on platelet function, together with the relatively small numbers of patients included in most randomized . . . [Full Text of this Article]


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Albumin versus hydroxyethyl starch in cardiopulmonary bypass surgery: a meta-analysis of postoperative bleeding
Mahlon M. Wilkes, Roberta J. Navickis, and William J. Sibbald
Ann. Thorac. Surg. 2001 72: 527-533. [Abstract] [Full Text] [PDF]



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M. M. Wilkes, R. J. Navickis, J. Avorn, and W. Winkelmayer
Hydroxyethyl Starch-Induced Postoperative Bleeding in Cardiac Surgery Patients: More Trials Needed?
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[Full Text] [PDF]


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