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Ann Thorac Surg 2001;71:1303-1304
© 2001 The Society of Thoracic Surgeons

Invited commentary

^a Department of Cardiovascular Surgery, Hôpital Bichat, 46, rue Henri-Huchard, 75018 Paris, France

e-mail: ccv-bloc.sec3@bch.ap-hop-paris.fr

In this elegant, carefully designed and well executed study, Li and coworkers have used a transgenic strain of mice developing severe atherosclerosis to assess the effects of preconditioning. The basic message conveyed in their article is that postischemic function is depressed to a greater extent in these hearts compared with nonatherosclerotic controls but that the protective effects of ischemic preconditioning are still manifested in this setting, thereby resulting in an improved recovery and a concomitant reduction in infarct size.

This study . . . [Full Text of this Article]

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