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Ann Thorac Surg 2001;71:397
© 2001 The Society of Thoracic Surgeons
a Department of Cardiothoracic Surgery, Uppsala University Hospital, S-751 85, Uppsala, Sweden
e-mail: christian.olsson@thorax.uas.lul.se
To the Editor
Royse and associates [1] reported their efforts to reduce postoperative neuropsychological dysfunction after coronary artery bypass grafting (CABG) in the May 2000 issue of The Annals of Thoracic Surgery. They conclude that the combined techniques of epiaortic ultrasound screening and exclusive Y grafting resulted in a low incidence of late neuropsychological dysfunction compared with standard management.
The study design and conduction raises several questions. Patients were not randomized to either group. This inevitably introduces the possibility of bias, regardless of apparent matching between groups. It is not stated whether the same surgical
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