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Ann Thorac Surg 2000;70:2118
© 2000 The Society of Thoracic Surgeons

Invited commentary

Todd Rosengart, MDa

a Division of Cardiothoracic Surgery, Evanston Northwestern Healthcare, Northwestern University Medical School, 2650 Ridge Ave, Evanston, IL 60201, USA

e-mail: trosengart@enh.org

A growing number of experimental studies continue to strengthen the evidence base suggesting the feasibility of administering angiogenic growth factor as a means of "biologically" revascularizing ischemic tissues. This strategy, termed therapeutic angiogenesis, has now been shown to induce the neovascularization of a wide variety of tissues. A number of studies, including this report by Sato and associates, suggest that this neovascularization response to growth factor delivery is sufficiently robust to . . . [Full Text of this Article]


Related Article

Efficacy of intracoronary versus intravenous FGF-2 in a pig model of chronic myocardial ischemia
Kaori Sato, Roger J. Laham, Justin D. Pearlman, Deborah Novicki, Frank W. Sellke, Michael Simons, and Mark J. Post
Ann. Thorac. Surg. 2000 70: 2113-2118. [Abstract] [Full Text] [PDF]






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