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Ann Thorac Surg 2000;70:954
© 2000 The Society of Thoracic Surgeons
Discussion
DR MARK D. IANNETTONI (Ann Arbor, MI): Id like to thank Dr Pompeo for the opportunity to discuss this paper and for sending it to us early. Hes added to the current literature suggesting that if patients are selected properly for lung volume reduction, they can achieve better relief from dyspnea and improved short-term benefit from surgery than from medical therapy.
In regard to the paper itself, the significant improvement that was seen with surgery obviously was better than that seen with medical therapy alone; however, there was a significant improvement with medical therapy as well.
I do have several questions for the authors with regard to the conclusions of their study and the study design. The first is related to patient selection. All of the current literature with respect to lung volume reduction surgery involves patients with nonbullous emphysema, either with or without a gradient. However, in their paper Dr Pompeo and colleagues state that patients with bullous emphysema were included in their study, and this is still one of the true exclusion criteria for lung volume reduction. My question is, what is your definition of bullous emphysema? Additionally, what percentage of your patients had bullous emphysema as their sole disease, and what percentage of these patients had unilateral disease?
The study also had an unusually large number of patients with unilateral disease, 13 of 30. Although
Related Article
Ann. Thorac. Surg. 2000 70: 948-953.
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