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Ann Thorac Surg 2000;70:888-889
© 2000 The Society of Thoracic Surgeons

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Discussion

Discussion

Discussion

DR VALAVANUR A. SUBRAMANIAN (New York, NY): This is indeed an excellent paper presented by the group from Boston University Medical Center. We have been interested in looking at the differences in the biological and pharmacologic characteristics of radial artery grafts in various groups of patients. It is a preliminary study we recently presented at the Society of Vascular Biology Annual Meeting last year.

People who are diabetic, who have smoked within a week of off pump coronary artery bypass (OPCAB), and those who have been on daily aspirin (325 mg), had decreased prostacyclin synthesis, higher intimal thickening, and reduced nitric oxide synthesis in their radial artery grafts. My question is, have you looked at the incidence of diabetes between the two groups and also the incidence of smoking, as thse preoperative risk factors may have an influence on the effectiveness of the drug, and also the tendency to spasm may be higher . . . [Full Text of this Article]

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Ann. Thorac. Surg. 2000 70: 883-888. [Abstract] [Full Text] [PDF]