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Ann Thorac Surg 2000;70:755
© 2000 The Society of Thoracic Surgeons

Invited commentary

Invited Commentary

Richard A. Jonas, MDa

a Department of Cardiac Surgery, Children’s Hospital, 300 Longwood Ave, Boston, MA, 02115 USA,

e-mail: richard.jonas@tch.harvard.edu

Invited commentary

The report by Pearl and colleagues from Cincinnati and Kansas City describes a retrospective study of acid production during deep hypothermic circulatory arrest and relates this to the pH and oxygen strategies applied during cardiopulmonary bypass. The authors conclude that the pH stat strategy with hyperoxia results in the lowest level of acid production and therefore is the optimal strategy. They speculate that reduced acid production is related to saturation of tissues with a higher total volume of oxygen which enables ongoing aerobic metabolism during deep hypothermic circulatory arrest.

This report provides further evidence . . . [Full Text of this Article]


Related Article

Hyperoxia for management of acid-base status during deep hypothermia with circulatory arrest
Jeffrey M. Pearl, Donald W. Thomas, Gary Grist, Jodie Y. Duffy, and Peter B. Manning
Ann. Thorac. Surg. 2000 70: 751-755. [Abstract] [Full Text] [PDF]





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