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Ann Thorac Surg 2000;69:1161
© 2000 The Society of Thoracic Surgeons

ORIGINAL ARTICLES: CARDIOVASCULAR

Invited commentary

Frank W. Sellke, MDa

a Division of Cardiothoracic Surgery, Beth Israel Deaconess Medical Center, 110 Francis St, LMOB 2A, Boston, MA 02215, USA

e-mail: fsellke@caregroup.harvard.edu


   Introduction
 
Kawasuji and colleagues describe the effects of intramyocardial injection of the angiogenic growth factor basic fibroblast growth factor on myocardial perfusion, function, and vascular density in a canine model of acute myocardial ischemia. Basic fibroblast growth factor increased regional blood flow, reduced thinning, and increased capillary and arteriolar densities in the myocardium subtended by the occluded left anterior descending artery. This is one of several recently . . . [Full Text of this Article]


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Therapeutic angiogenesis with intramyocardial administration of basic fibroblast growth factor
Michio Kawasuji, Hiroshi Nagamine, Masahiro Ikeda, Naoki Sakakibara, Hirofumi Takemura, Susumu Fujii, and Yoh Watanabe
Ann. Thorac. Surg. 2000 69: 1155-1161. [Abstract] [Full Text] [PDF]





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