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Ann Thorac Surg 2000;69:408
© 2000 The Society of Thoracic Surgeons
a Division of Cardiothoracic Surgery, University of North Carolina at Chapel Hill, 108 Burnett-Womack Building, CB #7065, Chapel Hill, NC 27599-7065, USA
Invited commentary
This study by Tanita and coworkers adds to a growing body of literature implicating activation of polymorphonuclear leukocytes (PMNs) as a contributing factor to pulmonary dysfunction. Using an isolated perfused rat lung model, the authors have investigated the impact of perfusion with human PMNs mechanically stimulated by gentle agitation in a glass vial. This resulted in increased CD18 integrin expression, assessed by immunofluorescence. The authors attempted to quantify capillary leak by modifying a method originally described by Aubrey Taylors group at the University of South Alabama. Capillary filtration coefficient has
Related Article
Ann. Thorac. Surg. 2000 69: 402-407.
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