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Ann Thorac Surg 1999;68:2058
© 1999 The Society of Thoracic Surgeons

Invited Commentaries

Harvey I. Pass, MDa

a Division of Cardiothoracic Surgery, Harper Hospital, 3990 John R, Suite 2102, Detroit, MI, USA 48201

e-mail: pass@cardiology.harper.wayne.edu

Invited commentary

There are a few papers every year that can potentially revolutionize the care of patients with lung cancer. This paper is one of them and should be listed as one of the classics from The Annals of Thoracic Surgery. Moreover, to have conceived the idea of bone marrow biopsy as a potential prognostic indicator in lung cancer in 1989 at a time when even "systemic mediastinal lymphadenectomy" was not even considered standard underscores the vision and genius of this thoracic group.

The findings in this manuscript that two or more micrometastases found on numerous bone-marrow biopsies is an independent predictor of overall survival from completely resected patients with lung cancer is, in my opinion, going to change our whole approach to the determination of the M status . . . [Full Text of this Article]


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Isolated tumor cells in bone marrow predict reduced survival in node-negative non-small cell lung cancer
Bernward Passlick, Boris Kubuschok, Jakob R. Izbicki, Olaf Thetter, and Klaus Pantel
Ann. Thorac. Surg. 1999 68: 2053-2058. [Abstract] [Full Text] [PDF]





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Copyright © 1999 by The Society of Thoracic Surgeons.