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Ann Thorac Surg 1997;64:1604-1605
© 1997 The Society of Thoracic Surgeons

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Discussion

Discussion

The first 20% of the full text of this article appears below.

See also page 1599.

DR ROBERT J. KEENAN (Pittsburgh, PA): Doctor Zwischenberger, I congratulate you; that is a lovely study.

I have several questions related more to some of the things that we have noted in our experience with ARDS, much of which has related to reperfusion injury after transplantation. The first question is, we have used venovenous ECMO as opposed to a venoarterial oxygenation circuit and found that to be relatively simple. Aside from the roller pump, what do you see as potential advantages of your AVCO2R over a straightforward venovenous ECMO circuit?

The second question is, we have found in reperfusion injury and in other models and other reasons for ARDS that oxygenation is a bigger problem than CO2 retention. Clearly you have a circuit that deals with CO2 but not oxygenation and you are compensating for that in your injury model by having a very high FiO2, which in itself may cause injury down the line. How do you deal with that?

. . . [Full Text of this Article]

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Total Arteriovenous CO₂ Removal: Simplifying Extracorporeal Support for Respiratory Failure

Robert L. Brunston, Jr, Joseph B. Zwischenberger, Weike Tao, Victor J. Cardenas, Jr, Daniel L. Traber, and Akhil Bidani
Ann. Thorac. Surg. 1997 64: 1599-1604. [Abstract] [Full Text]