|
|
||||||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||
Ann Thorac Surg 1997;63:1390
© 1997 The Society of Thoracic Surgeons
| The first 20% of the full text of this article appears below. |
See also page 1383.
DR JOHN C. WAIN (Boston, MA): Doctor Fujino and his colleagues are to be congratulated on an excellent study. My colleagues and I have actually used inhaled nitric oxide (NO) clinically in 4 donors for living-related lung transplantation. We have found excellent gas exchange in the recipients of these grafts, as you have in this experimental model. Fortunately, we have not had the opportunity to look at the gross histology of those lung grafts late postoperatively. I was wondering if you had noticed any histologic differences in the lungs in these canine models at the time of sacrifice, the ones that received NO versus the ones that did not receive NO?
DR FUJINO: Sorry, we did not make histologic assessment of these grafts.
DR G. ALEXANDER PATTERSON (St. Louis, MO): Doctor Wain, can I ask you how you measured the effect of inhaled NO in those living-related transplants?
DR WAIN: Well, there is no way for us to really be sure that NO administration was beneficial. However, the lung grafts worked exceedingly well in terms of gas exchange. Although they all had short ischemic times, averaging 65 minutes, after implantation the pulmonary venous oxygen tension from the grafts averaged about 475 mm Hg, which is significantly better than the graft gas exchange we have seen with any cadaveric transplantation. There was no evidence
Related Article
Ann. Thorac. Surg. 1997 63: 1383-1389.
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |