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Ann Thorac Surg 1996;62:1340-1341
© 1996 The Society of Thoracic Surgeons

Invited Commentary

Invited Commentary

Johannes Müller, MD, Roland Hetzer, MD, PhD

German Heart Institute Berlin, Augustenburger Platz 1, 13353 Berlin, Germany

The first 20% of the full text of this article appears below.

See also page 1337.

To our knowledge, seven articles have been published that report animal experiments of intramyocardial electrogram (IMEG) rejection monitoring on the basis of a decline of the QRS-complex amplitude [1–7]. This work from Everett and associates is the eighth article on this subject. All authors, except for Avitall and associates [2], who only used one bipolar ring electrode for recording of the IMEG, could find a correlation between alterations of the IMEG amplitude and the histologic findings of endomyocardial biopsy specimens, proving a sensitivity between 89% and 100% and a specificity between 77% and 90% in comparison with biopsy histology.

Three reasons could be identified for the decline of the IMEG amplitude during rejection episodes: (1) a reduced slew rate, (2) a diminished amplitude, . . . [Full Text of this Article]


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Noninvasive Diagnosis of Cardiac Allograft Rejection in an Orthotopic Canine Model
Jeffrey E. Everett, Mitchell N. Palmer, Jose Jessurun, and Sara J. Shumway
Ann. Thorac. Surg. 1996 62: 1337-1340. [Abstract] [Full Text]





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