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Ann Thorac Surg 1996;62:240-241
© 1996 The Society of Thoracic Surgeons

Discussion

Discussion

The first 20% of the full text of this article appears below.

See also page 233.

DR SHAF KESHAVJEE (Toronto, Ont, Canada): I congratulate Dr Van Raemdonck and associates on a very well thought-out, nicely planned, and carefully analyzed experiment. I appreciate the opportunity to have reviewed the manuscript before this.

Those of us who are interested in the study of non–heart-beating donors have come to realize that all non–heart-beating donors are not the same, and that factors occurring both before and after death can have significant impact on posttransplantation lung function. Clearly further careful study is required of non–heart-beating donors to identify the critical factors that will allow us to predict which lungs can be used for transplantation, and this study is one important first step along that line.

I have two questions. First, do you have any functional assessment data on the groups that you studied in this study to correlate your metabolic preservation with predicted postreperfusion lung function? Second, why did you choose to use Krebs-Henseleit as the flush control in this study?

DR VAN RAEMDONCK: Thank you, Dr Keshavjee. We appreciate your comments.

Indeed, not all non–heart-beating donors can be categorized in the same group. In a recent symposium held . . . [Full Text of this Article]


Related Article

Delay of Adenosine Triphosphate Depletion and Hypoxanthine Formation in Rabbit Lung After Death
Dirk E. M. Van Raemdonck, Nicole C. P. Jannis, Filip R. L. Rega, Paul R. J. De Leyn, Willem J. Flameng, and Toni E. Lerut
Ann. Thorac. Surg. 1996 62: 233-240. [Abstract] [Full Text]





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